Field experiments in winter wheat were carried out in to years with varying nitrogen and fungicide doses on field with large spatial variation in soils. Soils and crops were characterised using all relevant available sensor measurements. Measurements of soil texture using EM38 and crop status using remote sensing (RVI) could explain observed variations in yields, diseases and yield gain from fungicide application. An algorithm was developed to vary the fungicide dose depending on measurements of EM38 and RVI. A test of the algorithm showed that there were only small yield gains from use of sensor-based fungicide application compared with a standard uniform dose. However, the sensor-based application reduced fungicide deposition on the soil.